[pubmed] Eculizumab as a promising treatment in thymoma-associated myasthenia gravis

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Vélez-Santamaría V, et al. Ther Adv Neurol Disord 2020.

ABSTRACT

Myasthenia gravis is a chronic autoimmune disorder caused by antibodies directed against the neuromuscular junction. Some patients may have an associated thymoma, which confers a worse prognosis. Eculizumab, a monoclonal antibody that inhibits the activation of terminal complement, has recently been approved for the treatment of refractory generalized myasthenia gravis. This is an early case report of thymoma-associated refractory myasthenia gravis successfully treated with eculizumab in a real-world setting.

PMID:32655688 | PMC:PMC7331764 | DOI:10.1177/1756286420932035


Source: https://pubmed.ncbi.nlm.nih.gov/3265568 ... 9&v=2.10.1