[pubmed] Outcomes of juvenile myasthenia gravis: a comparison of robotic thymectomy with medication treatment

[RSS-Bot]

Ann Thorac Surg. 2021 Jan 19:S0003-4975(21)00091-6. doi: 10.1016/j.athoracsur.2020.12.045. Online ahead of print.

ABSTRACT

BACKGROUND: The study aims to compare the clinical outcomes of patients with juvenile myasthenia gravis (JMG) who underwent robotic thymectomy with that of those who only received medication therapy.

METHODS: We retrospectively reviewed patients who visited our institution for the diagnosis or treatment of MG with an age at onset younger than 18 years. Patients who underwent thymectomy comprised the surgical group and those who received only medication therapy comprised the nonsurgical group. The clinical outcomes were assessed according to the Myasthenia Gravis Foundation of America Post Intervention Status.

RESULTS: Forty-seven patients (35 female: 12 male) were included as the surgical group and 20 patients (15 female: 5 male) comprised the nonsurgical group. Significant differences were observed between the surgical and nonsurgical groups in antibody against acetylcholinesterase receptor (91.5% versus 65%, p=0.012), disease duration (16 [7-25] months versus 96 [42-480] months, p

Source: https://pubmed.ncbi.nlm.nih.gov/3348216 ... 5&v=2.14.2