Exercices dans la myasthénie gravis: Une étude de faisabilité de l'entraînement aérobie et de résistance.
Posté : 25 janv. 2017 09:55
Lu sur https://www.ncbi.nlm.nih.gov/pubmed/28085204
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Exercise in myasthenia gravis: A feasibility study of aerobic and resistance training
Rahbek MA1, Mikkelsen EE1, Overgaard K1, Vinge L2, Andersen H2, Dalgas U1.
Muscle Nerve. 2017 Jan 13. doi: 10.1002/mus.25552. [Epub ahead of print]
Abstract
- INTRODUCTION:
It has not been established whether progressive resistance training (PRT) and aerobic training (AT) are feasible and efficient in myasthenia gravis (MG).
- METHODS:
Fifteen subjects with generalized MG (MGFA II - IV) were randomly assigned to 20 training sessions during 8 weeks of either progressive resistance training or aerobic training. Feasibility was evaluated based on adherence, drop-out rate, adverse events, and Quantitative MG score.
- RESULTS:
Twelve subjects (MGFA II, n=11; MGFA III, n=1) completed the intervention with a mean adherence of 95% ± 8. One dropout (PRT) could potentially be related to PRT. Both groups reported adverse events, including bulbar symptoms (n=2) and increased fatigue (n=3), but no change in QMG-score was observed in either group. The PRT group showed increases in maximal strength and functional capacity.
- DISCUSSION:
Eight weeks of moderate to high intensity AT and PRT were feasible for most patients with mild MG. Maximal strength and functional capacity increased in the PRT group.