Lu sur https://www.ncbi.nlm.nih.gov/pubmed/28414153
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Inflammatory myopathy associated with myasthenia gravis with and without thymic pathology: Report of four cases and literature review.
Santos E1, Coutinho E2, da Silva AM3, Marinho A4, Vasconcelos C5, Taipa R6, Pires MM7, Gonçalves G8, Lopes C9, Leite MI10.
PMID: 28414153 DOI: 10.1016/j.autrev.2017.04.009
the association of myasthenia gravis (MG) and inflammatory myopathy is rare and often only one of the diseases is diagnosed. Thymus pathology may be in the origin of such disease association.
we described four patients with both MG and inflammatory myopathy.
these cases correspond to 2.3% of our MG cohort. Case 1: MG, polymyositis and thymolipoma; case 2: MG and necrotizing myopathy without thymic pathology on a background of scleroderma, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, telangiectasia (CREST); case 3: MG and dermatomyositis without thymic pathology; case 4: MG and dermatomyositis with type C thymoma.
the recognition of these neuromuscular co-morbidities contributes to (i) understanding their pathogenic mechanisms, (ii) developing better management approaches and (iii) further improving disease outcomes.