Lu sur :https://www.ncbi.nlm.nih.gov/pubmed/29239825
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Lien vers Google trad https://translate.google.fr/translate?h ... 2F29239825Palpebral portion of the orbicularis oculi muscle to repetitive nerve stimulation testing: A potential assessment indicator in patients with generalized myasthenia gravis.
Yan C1, Song J1, Pang S2, Yi F3, Xi J1, Zhou L1, Ding D4, Wang W5, Qiao K6, Zhao C7.
J Clin Neurosci. 2017 Nov 24. pii: S0967-5868(17)31486-8. doi: 10.1016/j.jocn.2017.11.005.
Repetitive nerve stimulation (RNS) is a valuable diagnostic method for myasthenia gravis (MG).
However, its association with clinical severity was scarcely studied.
We reviewed medical records and retrospectively enrolled 121 generalized MG patients.
Sensitivity of different muscles to RNS and clinical scoring systems was evaluated.
RNS testing revealed facial muscles have the highest positive rate, followed by proximal muscles and distal muscles, with the palpebral portion of the orbicularis oculi muscle most sensitive.
Amplitude decrement of compound muscle action potential (CMAP) in the palpebral portion of the orbicularis oculi muscle is related to quantitative myasthenia gravis (QMG) scores, MG-specific manual muscle testing (MMT) scores and myasthenia gravis-related activities of daily living (MG-ADL) scores.
We suggest that RNS testing of the palpebral portion of the orbicularis oculi muscle is a potential assessment indicator in patients with generalized MG.