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Caractéristiques, incidence et résultats des patients admis à l'unité de soins intensifs atteints de myasthénie grave.

Posté : 08 févr. 2018 19:28
par Pboulanger
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:arrow: Lu sur :https://www.ncbi.nlm.nih.gov/pubmed/29413729

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Characteristics, incidence, and outcome of patients admitted to the intensive care unit with myasthenia gravis.
Al-Bassam W1, Kubicki M1, Bailey M2, Walker L3, Young P4, Pilcher DV5, Bellomo R6.
J Crit Care. 2018 Jan 7;45:90-94. doi: 10.1016/j.jcrc.2018.01.003. [Epub ahead of print]



Abstract


  • BACKGROUND:

    There are limited data on the characteristics, incidence, and mortality of patients with myasthenia gravis (MG) admitted to the ICU.
  • AIMS:

    To study the epidemiology, characteristics and outcome of patients with MG in Australian and New Zealand (ANZ) ICUs over a decade.
  • METHODS:

    We performed a retrospective observational, cross sectional study of data from the Australian and New Zealand Intensive Care Society (ANZICS) Adult Patient Database (APD). We collected data on all adult patients admitted with a primary diagnosis of MG to 159 Australian and 19 New Zealand ICUs between January 1, 2005 and December 31, 2015.We extracted detailed relevant data and performed statistical assessment.
  • RESULTS:

    We identified 245 patients admitted to ICU with the primary diagnosis of MG, with an incidence increasing from 1 to 2.5 per thousand ICU admissions (P<0.0001) and from 1 to 2.2 per million people (P=0.02). Mean age was 60years with more patients being female (53.7% vs 47.3%) and 91 (37.1%) patients received mechanical ventilation. Hospital mortality occurred in 13 (5.3%) patients with a mortality rate lower than in other ICU patients.
  • CONCLUSIONS:

    In ANZ, the ICU and population incidence of MG has increased over the last decade. However, its mortality rate was low.
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