Page 1 sur 1

Une augmentation de la proportion de cellules Tc17 et Th17 et de leur réduction significative après thymectomie ...

Posté : 08 févr. 2018 19:32
par Pboulanger
:hi:

:arrow: Lu sur :https://www.ncbi.nlm.nih.gov/pubmed/29414833

[ligne][/ligne]

Traduction disponible directement en cliquant en bas à droite de ce message sur l'expression Traduire en

Image

[ligne][/ligne]

Increased Proportion of Tc17 and Th17 Cells and Their Significant Reduction after Thymectomy May Be Related to Disease Progression in Myasthenia Gravis.
Hosseini M1, Robat-Jazi B, Shaygannejad V, Naffisi S, Mirmossayeb O, Rezaei A, Mansourian M, Esmaeil N.
Neuroimmunomodulation. 2018 Feb 8. doi: 10.1159/000486037. [Epub ahead of print]


Abstract

  • OBJECTIVE:

    Myasthenia gravis (MG) is an autoimmune disease mediated by autoantibodies against the neuromuscular junction. The thymus has an important role in the pathogenesis of MG because most patients have thymic pathology, and thymectomy (TE) can reduce the severity of the disease.
  • METHODS:

    In this study, the frequency of Th17 and Tc17 cells was studied in 12 MG patients (pre-TE and 6 months post-TE) and in 12 healthy controls (HC).
  • RESULTS:

    The frequency of Tc17 cells in the pre-TE patients was significantly higher than in the HC (p < 0.05), and after TE, these cells had significantly decreased compared to before TE (p < 0.05). The frequency of Th17 cells in pre-TE patients was significantly higher than in the HC (p < 0.05), and after TE, these cells had significantly decreased compared to before TE (p < 0.05).
  • CONCLUSION:

    Our findings indicated a possible role of Tc17 and Th17 in MG pathogenesis.


Message d' un membre de l'équipe technique
Pour les utilisateurs d'I-phone
ci-dessous le lien vers Google Trad

https://translate.google.fr/translate?h ... 2F29414833
Message d' un membre de l'équipe technique
Nous utilisons des services automatiques de traduction fournis
par Yandex ou Google.
Soyez vigilant sur le risque de contre-sens inhérent à ce genre d'outils.