Lu sur :https://www.ncbi.nlm.nih.gov/pubmed/29984007
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Drug Hypersensitivity due to Azathioprine with Elevated Procalcitonin.
Ahuja T1, Chung FR2, Ruiz-Maya T3.
Case Rep Dermatol Med. 2018 Jun 10;2018:2648325. doi: 10.1155/2018/2648325. eCollection 2018.
Abstract
We present a case of azathioprine hypersensitivity presenting as sepsis with elevated procalcitonin in a 68-year-old man with myasthenia gravis.
The patient presented with fever, chills, nausea, vomiting, and headache.
He developed numerous 1 cm erythematous papules over his upper torso.
Infectious workup including bacteriological tests and microbial cultures was negative and a skin biopsy was performed which revealed suppurative folliculitis with eosinophils, consistent with drug hypersensitivity.
Notably, acute phase reactants including C-reactive protein and procalcitonin were elevated upon presentation, likely secondary to drug hypersensitivity.
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