[SMLE] Transition of Japanese clinical guidelines for myasthenia gravis

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Rinsho Shinkeigaku. 2023 May 17. doi: 10.5692/clinicalneurol.cn-001853. Online ahead of print.

ABSTRACT

The Japanese clinical guidelines for myasthenia gravis (MG) were revised in 2022. The major revision points in these guidelines are as follows. 1) A description of Lambert-Eaton myasthenic syndrome (LEMS) was included for the first time. 2) Revised diagnostic criteria of both MG and LEMS are proposed. 3) A high-dose oral steroid regimen with escalation and de-escalation schedule is not recommended. 4) Refractory MG is defined. 5) The use of molecular-targeted drugs is included. 6) MG is divided into six clinical subtypes. 7) Treatment algorithms for both MG and LEMS are presented.

PMID:37197966 | DOI:10.5692/clinicalneurol.cn-001853


Source: https://pubmed.ncbi.nlm.nih.gov/3719796 ... t6+86293ac