[Pubmed] Pearls & Oy-sters: Thyroid-Associated Ophthalmopathy and Transient Neuromuscular Junction Disorder Due to Grave

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Neurology. 2024 Apr 23;102(8):e209282. doi: 10.1212/WNL.0000000000209282. Epub 2024 Mar 21.

ABSTRACT

The concomitant presentation of thyroid-associated ophthalmopathy (TAO) and ocular myasthenia gravis is well documented. In the course of Graves disease (GD), symptomatic transient neuromuscular junction disorder may occur due to the effect of thyroid hormones at the neuromuscular synapse. Diagnostic clues are the clinical and electrophysiologic remission synchronous with restoration of euthyroidism. Furthermore, the occurrence of thymic hyperplasia in GD poses further diagnostic and therapeutic considerations. These points are discussed in the case report of a 43-year-old male patient suffering from TAO and transient neuromuscular junction disorder due to GD.

PMID:38513158 | DOI:10.1212/WNL.0000000000209282


Source: https://pubmed.ncbi.nlm.nih.gov/3851315 ... t9+e462414