Lu sur :https://www.ncbi.nlm.nih.gov/pubmed/29212280
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Influence of body mass index on postoperative complications after thymectomy in myasthenia gravis patients.
Liu XD1,2, Shao MR1, Sun L1, Zhang L1, Jia XS3,4, Li WY1.
Oncotarget. 2017 Jul 12;8(55):94944-94950. doi: 10.18632/oncotarget.19189. eCollection 2017 Nov 7.
Abstract
- Objectives:
It is not clear whether being overweight or obese influences postoperative complications in myasthenia gravis (MG) patients. We retrospectively investigated an association between body mass index (BMI) and postoperative complications in MG.
- Materials and Methods:
Fifty-nine MG patients who had undergone transsternal thymectomy were classified as low or high BMI based on the criteria for Asian-Pacific populations. An association between BMI and complications was analyzed.
- Results:
MG patients with high BMI had significantly higher rates of major adverse complications (P = 0.033), postoperative respiratory failure (P = 0.045), and longer postoperative hospitalization (P = 0.005). The optimal cutoff value of BMI for postoperative respiratory failure was 23.3 kg/m2, with a sensitivity of 75.0% and a specificity of 64.7% (P = 0.046).
- Conclusions:
MG patients with a BMI indicating overweight or obesity have a higher risk of postoperative complications after thymectomy. Thus, close monitoring must be performed when surgery is necessary.
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