Lu sur :https://www.ncbi.nlm.nih.gov/pubmed/29466829
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Gender and Quality of Life in Myasthenia Gravis Patients from the Myasthenia Gravis Foundation of America Registry.
Lee I1, Kaminski HJ2, Xin H3, Cutter G4.
Muscle Nerve. 2018 Feb 21. doi: 10.1002/mus.26104.
Quality of life (QOL) has been poorly characterized among patients with myasthenia gravis (MG) other than assessments performed within the clinical setting.
Patients age >=18 years who were diagnosed with MG and registered with the MG patient registry between 7/1/2013 and 6/30/2016 were included. Demographic information, disease related history, and QOL were compared between men and women using multivariable analysis.
A total of 1,315 subjects (827 women) were included. Women were significantly younger, had a younger age at symptom onset, and were more likely to have thymoma and thymectomy. MG-QOL15 was significantly worse in women. MG-QOL15 score was comparable between women who had thymectomy and men with or without thymectomy.
QOL among MG patients is worse in women compared to men, but this disparity is eliminated in women who have undergone thymectomy.