[pubmed] Comparison of the Single Simple Question and the Patient Acceptable Symptom state in Myasthenia Gravis
Posté : 15 juin 2020 12:00
Menon D, et al. Eur J Neurol 2020.
ABSTRACT
BACKGROUND: The Single Simple Question (SSQ) is a simple and validated question asking what percentage of normal a patient feels with respect to their myasthenia gravis (MG), with 100% being normal. Patient Acceptable Symptom States (PASS), are based on a dichotomous 'Yes' or 'No' response, asking whether a patient is satisfied overall with their current status and thus, measures holistic satisfaction with their MG state. Both are patient-reported self assessments but assess different dimensions of MG.
OBJECTIVE: To determine thresholds for the SSQ when patients with MG achieve an acceptable PASS status.
METHODS: We performed a retrospective chart review of consecutive MG patients attending a neuromuscular clinic and extracted SSQ and PASS responses, demographic, clinical and serological characteristics and disease severity by the myasthenia gravis impairment index (MGII).
RESULTS: 157 consecutive patients were identified: 43 (27.4%) patients responded 'No' to the PASS question. Between the PASS 'Yes'/ 'No' groups, only SSQ (87.5 ±13.4 vs 52.3 ±23.3; p
Source: https://pubmed.ncbi.nlm.nih.gov/3253782 ... 22&v=2.8.0