[pubmed] Prospective study of stress, depression and personality in myasthenia gravis relapses

Intégration des publications parues sur PUBMED
Répondre
Avatar de l’utilisateur

Auteur du sujet
RSS-Bot
Ami(e) d'Argent
Ami(e) d'Argent
Messages : 99
Inscription : 31 mai 2020 09:57
    Macintosh Safari
Zodiaque :
Âge : 20

[pubmed] Prospective study of stress, depression and personality in myasthenia gravis relapses

Message par RSS-Bot »


Bogdan A, et al. BMC Neurol 2020.

ABSTRACT

BACKGROUND: Psychopathology and personality traits may influence the course of autoimmune disorders. With this prospective longitudinal cohort study, we aimed to assess personality, stress and depression in myasthenia patients who relapse and those who remain stable or improve (non-relapsers).

METHOD: We collected data from 155 consecutive adult patients with confirmed MG attending the Neuromuscular Clinic, Toronto General Hospital, between March 2017 and July 2018, for this study. Patients were assessed at baseline and 6 months, or at the time of MG relapse. At both visits, the patients were assessed clinically and were asked to complete self-administered questionnaires for disease severity, chronic stress and depression. Personality type was assessed at baseline only. Relapsing patients were defined as those patients with MGII score increasing by more than 5.5 points from visit 1 to visit 2.

RESULTS: Relapsers had higher baseline scores for depression (p = 0.01) and the change in disease severity correlated with the change in depression score (r = 0.2534, p = 0.0015, 95% CI: 0.098 0.3961). Higher levels of stress at baseline and neuroticism predicted higher relapse rates (p = 0.01 and p < .0001, respectively). In the linear regression model, with change of the MGII score as the dependent variable, change in depression scores (p = 0.0004) and age (p = 0.03) predicted change in disease severity.

CONCLUSIONS: Since emotional factors and personality type may influence MG, attention to these factors might improve care in MG patients.

PMID:32600271 | DOI:10.1186/s12883-020-01802-4

Image


Source: https://pubmed.ncbi.nlm.nih.gov/3260027 ... 21&v=2.9.4
Pour obtenir la traduction en français,
cliquez sur le bouton situé dans la barre des menus en haut de cette page 

Image


Pour les donateurs, si cet article vous intéresse, nous pouvons faire l’acquisition d'un tiré-à-part.
Merci d'en faire la demande sur association.amis-modo@myasthenie.com


Nous prenons en charge le coût de cette demande (en général +/- USD 40,00$) dans la limite de nos ressources.

Bonne lecture...

Répondre

Revenir à « Echos de la recherche »