[pubmed] AChR-and MuSK-positive myasthenia gravis: Double trouble
Posté : 11 sept. 2020 12:00
J Neuroimmunol. 2020 Sep 3;348:577364. doi: 10.1016/j.jneuroim.2020.577364. Online ahead of print.
ABSTRACT
This is a report of an early onset AChR-and MuSK-positive myasthenia gravis. The double seropositivity was detected at the onset of the disease and persisted during 3.5 years follow-up despite the chronic immunotherapy and thymectomy. It is the second reported case of this rare immunological coexistence with sufficient follow-up and available clinical details. At the detection of double positive AChR and MuSK Abs, the treating physician often feels unsecure about the optimal treatment strategy and the long-term prognosis. The detailed clinical record and the long observation of these rare cases, are mandatory for best management in clinical practice.
PMID:32916523 | DOI:10.1016/j.jneuroim.2020.577364
Source: https://pubmed.ncbi.nlm.nih.gov/3291652 ... 9&v=2.11.5