[Pubmed] New-onset myasthenia gravis confirmed by electrodiagnostic studies after a third dose of SARS-CoV-2 mRNA-1273 v
Posté : 05 août 2022 12:00
Am J Phys Med Rehabil. 2022 Aug 2. doi: 10.1097/PHM.0000000000002076. Online ahead of print.
ABSTRACT
COVID-19 vaccine-related pathology is a rare occurrence with few reported cases. We report on a case of a 60-year-old man experiencing symptoms of dysphagia, dysarthria, diplopia, and weakness with onset six days after receiving a third full dose of SARS-CoV-2 vaccine (mRNA-1273 vaccine) in August 2021, which he received outside of the CDC recommended guidelines, at four months after his second dose of the Moderna vaccination course in March 2021. FDA Emergency Use Authorization for mRNA-1273 booster was established in October 2021.Over the next month, the patient's symptoms progressed including his inability to swallow, requiring hospitalization due to dehydration and malnutrition. Evaluation including laboratory prompted referral for electrodiagnostic studies consisting of repetitive nerve stimulation studies and needle electromyography, confirming a case of new onset bulbar myasthenia gravis.
PMID:35930797 | DOI:10.1097/PHM.0000000000002076
Source: https://pubmed.ncbi.nlm.nih.gov/3593079 ... 4&v=2.17.7