[Pubmed] Generalized myasthenia gravis: Clinical trials to watch
Posté : 11 sept. 2026 12:00
Med. 2026 Sep 11;7(9):101270. doi: 10.1016/j.medj.2026.101270.
ABSTRACT
Generalized myasthenia gravis is undergoing a highly dynamic phase of therapeutic development, with ongoing trials increasingly targeting upstream immune mechanisms. This Trial Watch highlights six studies evaluating B cell survival modulation, lymphocyte-directed immune reconstitution, BCMA- and CD19-directed CAR-T cell therapy, T cell engagement, and response-guided combination therapy, and considers their implications for future treatment strategies.
PMID:42727567 | DOI:10.1016/j.medj.2026.101270
Source: https://pubmed.ncbi.nlm.nih.gov/4272756 ... 0&v=2.20.1