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Efficacy and Safety of the TCM Qi-Supplementing Therapy in Patients with Myasthenia Gravis: A Systematic Review and Meta-Analysis.
Yang XQ1, Liu L2,3, Yang WY4, Dong HH3, Yang YR1, Li Y3.
Evid Based Complement Alternat Med. 2017;2017:6512572. doi: 10.1155/2017/6512572. Epub 2017 Dec 3.
Abstract
- Background:
The Traditional Chinese Medicine (TCM) Qi-supplementing therapy has been used widely for treating myasthenia gravis (MG) in China. The purpose of this meta-analysis was to evaluate the efficacy and safety of Qi-supplementing therapy as an adjunctive therapy in MG patients.
- Methods:
Seven electronic databases were searched through June 2016. Randomized controlled trials (RCTs) evaluating the add-on effect of Qi-supplementing therapy in MG patients were included. The outcome measures were the total effective rate, relapse rate, and adverse events.
- Results:
Twenty-three RCTs involving 1,691 MG patients were included. The included studies were of low-to-moderate quality. Meta-analysis showed that Qi-supplementing therapy combined with Western medicine (WM) significantly improved the total response rate and reduced the relapse risk during 6-24 months of follow-up. Subgroup analysis showed that Qi-supplementing therapy only affected the total response rate within the first 6 months of treatment. Moreover, the rate of adverse events was lower with the addition of Qi-supplementing therapy to WM than with WM only.
- Conclusions:
Short-term Qi-supplementing therapy combined with WM appears to be superior to WM for improving the total response rate and reducing the relapse rate. However, more high-quality RCTs are warranted owing to methodological flaws of previous trials.
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Le Qi, dans la médecine traditionnelle chinoise,est "la force de vie circulante". Le concept du qi est connu sous de nombreux noms à travers le monde. C'est ce qu'on appelle "prana" ou shaki en Inde, "ki" au Japon, "pneuma" en Grèce, "Great Spirit" par de nombreux Amérindiens, et "ashe" par certains groupes africains.
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