Lu sur : https://www.ncbi.nlm.nih.gov/pubmed/31478207[hr]
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Muscle Nerve. 2019 Sep 3. doi: 10.1002/mus.26694. [Epub ahead of print]
Employment in Refractory Myasthenia Gravis: An Mgfa Registry Analysis.
Harris L1, Aban IB2, Xin H3, Cutter G2.
Abstract
INTRODUCTION:
Labor-market participation is potentially very difficult for patients with refractory myasthenia gravis (MG). Here, employment status and work absences are compared between refractory and non-refractory MG.
METHODS:
Adults (aged 18-64 years; diagnosed ≥2 years previously) were included if enrolled in the MG Foundation of America Patient Registry during July 2013-February 2018.
RESULTS:
Seventy-six patients (9.2%) had refractory and 749 (90.8%) had non-refractory disease; demographic data did not differ between groups. Relative to the non-refractory group, the refractory group were more than twice as likely to work fewer hours per week (odds ratio [95% confidence interval]: currently employed, 2.777 [1.640-4.704]; employed over previous 6 months, 2.643 [1.595-4.380]), but those employed were not more likely to be absent from work.
DISCUSSION:
Because absence from the labor market adversely affects quality of life and personal finances, these findings reaffirm the considerable disease burden associated with refractory MG.
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