[pubmed] Therapeutic plasma exchange in neurological diseases: Eleven years experience a tertiary care center in Turkey

[RSS-Bot]

Ther Apher Dial. 2021 Jun 26. doi: 10.1111/1744-9987.13703. Online ahead of print.

ABSTRACT

OBJECTIVE: Therapeutic plasma exchange (TPE) is an apheresis procedure in which plasma is separated from the blood cellular components ex vivo, allocated, and replaced with another plasma or a plasma-replacing fluid. This study aimed to define the rate of complications and determine TPE distribution in various neurological diseases.

MATERIALS AND METHODS: Our study is a retrospective analysis of neurologic diseases requiring TPE between 2008 and 2019 that were selected using the medical records of neurology departments and apheresis units database.

RESULTS: We performed 1459 TPE procedures on 207 patients between 2008 and 2019. TPE Procedure is most frequently applied in patients with Myasthenia-Gravis syndrome (34.7%). The complication ratio was 1.6% from a total of 1459 TPE procedures. The most commonly specified adverse event was allergic reactions 11 (5.3%), followed by hypotension 6 (2.9%).

CONCLUSION: TPE was safe and tolerable, with manageable complications in experienced hands. This article is protected by copyright. All rights reserved.

PMID:34173719 | DOI:10.1111/1744-9987.13703


Source: https://pubmed.ncbi.nlm.nih.gov/3417371 ... 1&v=2.14.4