[Pubmed] Metastatic neuroendocrine tumors mimicking as primary ocular disease

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Am J Ophthalmol Case Rep. 2022 Feb 15;26:101425. doi: 10.1016/j.ajoc.2022.101425. eCollection 2022 Jun.

ABSTRACT

PURPOSE: To report two cases of metastatic neuroendocrine tumors masquerading as primary ocular disease.

OBSERVATIONS: Case 1 is a 38-year-old man who was referred with subacute onset diplopia and fluctuating ptosis suggestive of myasthenia gravis. Case 2 is a 21-year-old man who presented with blurry vision and was found to have a pigmented ciliary body mass and retinal detachment suggestive of uveal melanoma. Both patients were ultimately diagnosed with metastatic neuroendocrine tumors.

CONCLUSIONS AND IMPORTANCE: Neuroendocrine tumors, though rare and infrequently metastatic to the eye and orbit, can initially present with ocular signs. A broad differential and careful consideration of ocular and systemic symptoms are critical in such challenging cases.

PMID:35243162 | PMC:PMC8858882 | DOI:10.1016/j.ajoc.2022.101425


Source: https://pubmed.ncbi.nlm.nih.gov/3524316 ... 7&v=2.17.5