[Pubmed] Survival and Autoimmune Risks Post-Thymectomy: Insights from Myasthenia Gravis and Non-MG Populations (P1-11.02

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Neurology. 2025 Apr 8;104(7_Supplement_1):4467. doi: 10.1212/WNL.0000000000211695. Epub 2025 Apr 7.

ABSTRACT

OBJECTIVE: We aimed to test this hypothesis in thymectomy patients with and without myasthenia gravis (MG).

BACKGROUND: The thymus is necessary to maintain immune competence and overall health, recently it was shown that thymic removal could potentially disrupt these functions.

DESIGN/METHODS: This retrospective study analyzed clinical, laboratory, and radiological data from January 1, 2010, to November 30, 2023. Patients were grouped into MG thymectomy, non-MG thymectomy, and thoracoscopic surgery without thymectomy.

RESULTS: We identified a total of 178 patients (n=41 MG, n=65 non-MG, n=72 no thymectomy). MG-thymectomy group median age was 45.6 (range: 22-79 years) versus 59.8 years (range: 19-85) in the no-MG group; p

Source: https://pubmed.ncbi.nlm.nih.gov/4019418 ... t9+e462414