[Pubmed] Single-sterilization modified-position robotic-assisted McKeown esophagectomy versus minimally invasive approac

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J Thorac Dis. 2026 Mar 31;18(3):200. doi: 10.21037/jtd-2025-1-2462. Epub 2026 Mar 24.

ABSTRACT

BACKGROUND: Surgical resection remains a key component of multimodal therapy for patients with resectable or locally advanced esophageal squamous cell carcinoma (ESCC) after neoadjuvant chemoimmunotherapy (nCIT). This study compared the safety and efficacy of single-sterilization modified-position robotic-assisted esophagectomy (SM-RAE) with conventional minimally invasive esophagectomy (MIE), focusing on perioperative outcomes, composite adverse events, electronic patient-reported outcomes (ePROs), and short-term oncologic results.

METHODS: This single-center retrospective study included 137 ESCC patients who underwent McKeown esophagectomy after nCIT between January 2022 and December 2024. Of them, 36 received SM-RAE and 101 received MIE. Baseline characteristics, perioperative indicators, composite adverse events (operative time ≥330 min, intraoperative blood loss ≥400 mL, conversion to open, non-R0 resection, or Clavien-Dindo grade ≥ III complications), ePROs (pain, cough, distress, dysphagia, and dyspnea), and short-term survival outcomes were analyzed. Propensity score matching (PSM) was applied to balance baseline variables, and comparisons were repeated after matching.

RESULTS: Compared with MIE, SM-RAE resulted in shorter operative time (270 vs. 295 min, P

Source: https://pubmed.ncbi.nlm.nih.gov/4198831 ... t6+133c1fe