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Effect of thymectomy for thymic atrophy in myasthenia gravis: A retrospective study on 93 patients.
Nakahara K1, Nakane S2, Nakajima M3, Yamashita S4, Mori T5, Ando Y6.
J Neuroimmunol. 2017 Jan 12. pii: S0165-5728(16)30355-1. doi: 10.1016/j.jneuroim.2017.01.005. [Epub ahead of print]
To clarify the efficacy of thymectomy among myasthenia gravis (MG) patients with and without thymoma. We classified MG patients who underwent thymectomy into 3 groups, such as thymic atrophy group, thymic follicular hyperplasia (TFH) group and thymoma group.
We compared the data of clinical features and postoperative prognosis at very short-term, short-term, and medium-term.
The clinical course of MG patients with atrophic thymus after thymectomy was even better than those of TFH or thymoma, in this retrospective study.
However, we found no significant differences in the comparison of mean dose of prednisolone between the 3 groups at each time point.