[Pubmed] Population-Based Study of Nonelective Postpartum Readmissions in Women With Stroke, Migraine, Multiple Sclerosi

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Neurology. 2022 Feb 15:10.1212/WNL.0000000000200007. doi: 10.1212/WNL.0000000000200007. Online ahead of print.

ABSTRACT

BACKGROUND AND OBJECTIVES: To compare maternal obstetric complications and non-elective readmissions in women with common neurological comorbidities (WWN) versus women without neurological disorders.

METHODS: We performed a retrospective cohort study of index characteristics and acute postpartum, non-elective rehospitalizations from the 2015-2017 National Readmissions Database using International Classification of Diseases, Tenth Revision codes. Wald chi-squared testing compared baseline demographic, hospital, and clinical characteristics and postpartum complications between WWN [to include prior stroke, migraine, multiple sclerosis (MS), and myasthenia gravis (MG)] and controls. Multivariable logistic regression models examined odds of postpartum complications and non-elective readmissions within 30 and 90 days for each neurological comorbidity compared to controls (alpha = 0.05).

RESULTS: A total of 7,612 women with prior stroke, 83,430 women with migraine, 6,760 women with MS, 843 women with MG, and 8,136,335 controls met the criteria for index admission after viable infant delivery. WWN were more likely than controls to have inpatient diagnoses of edema, proteinuria, hypertensive disorders and to have received maternal care for poor fetal growth. The adjusted odds of a Centers for Disease Control and Prevention (CDC) severe maternal morbidity indicator (SMM) were greater for women with prior stroke: AOR 8.53, 95% CI 7.24-10.06, migraine: AOR 2.04, 95% CI 1.85-2.26 and MG: AOR 4.45, 95% CI 2.45-8.08 (all p

Source: https://pubmed.ncbi.nlm.nih.gov/3516901 ... 6&v=2.17.5