[Pubmed] Is Video-Oculography a Predictive Test for Myasthenia Gravis with Ocular Symptoms?

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Neurol India. 2022 Jan-Feb;70(1):80-86. doi: 10.4103/0028-3886.336330.

ABSTRACT

BACKGROUND AND OBJECTIVE: The aim of this study was to evaluate the contribution of extraocular muscle function testing with video-oculography (VOG), which is a noninvasive and easily applicable method of recording eye movement with digital cameras, to the diagnosis of myasthenia gravis (MG) in patients without any clinical eye movement abnormalities.

METHODS AND MATERIALS: The study included 18 patients prediagnosed with ocular MG: MG Group (N = 7) with abnormal, and non-MG Group (N = 11) with normal single-fiber electromyography. Control group included 50 healthy volunteers. Ocular movements were recorded with the EyeSeeCam VOG device.

RESULTS: The inward latency of the 10° horizontal saccade and the downward latency of the 10° vertical saccade were significantly delayed; and the downward amplitude of the 10° vertical saccade was significantly lower in the MG group. Receiver operating characteristic curve analyses showed high specificity values for the discrimination of MG patients.

CONCLUSIONS: This study supports the usefulness of the VOG device in revealing subclinical extraocular muscle involvement in MG.

PMID:35263858 | DOI:10.4103/0028-3886.336330


Source: https://pubmed.ncbi.nlm.nih.gov/3526385 ... 5&v=2.17.6