[Pubmed] Unveiling the uncommon: a captivating case of multiple autoimmune syndrome

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Arch Clin Cases. 2024 Oct 9;11(3):83-85. doi: 10.22551/2024.44.1103.10293. eCollection 2024.

ABSTRACT

Multiple autoimmune syndrome (MAS) is characterized by the coexistence of three or more autoimmune diseases. We are reporting a unique case of MAS, presented as a Myasthenia Gravis exacerbation, found to have unexpected sero-abnormalities. A 39-year-old female presented with complaints of progressive difficulty swallowing of solids and liquids, droopy eyelids, and facial weakness. Physical examination revealed bilateral ptosis and proptosis, slow-muffled speech, loss of EOM, inability to smile, puff cheeks, clench teeth, or protrude tongue and an asymmetrical shoulder shrug. Motor tone was normal except ⅘ in the left arm and ⅗ in left hand with loss of flexion at left DIP joints. Acetylcholine receptor binding antibodies, ANA, Antithyroid peroxidase, antithyroglobulin and Anti SS-A were positive. MAS, while not a life-threatening condition, greatly degrades patients' quality of life. We recommend that when you encounter patients with one or more autoimmune disorder, you consider MAS in your differential.

PMID:39479257 | PMC:PMC11520170 | DOI:10.22551/2024.44.1103.10293


Source: https://pubmed.ncbi.nlm.nih.gov/3947925 ... t9+e462414