[Pubmed] Ocular neurolymphomatosis: a case report and systematic review of ocular cranial nerve neurolymphomatosis

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Orbit. 2025 May 21:1-6. doi: 10.1080/01676830.2025.2505501. Online ahead of print.

ABSTRACT

Neurolymphomatosis is a rare manifestation of lymphoma. Neurolymphomatosis involving ocular cranial nerves of II, III, IV, and VI remains a poorly characterized disease entity. The authors report a case of cranial nerve III neurolymphomatosis with simultaneous extraocular muscle infiltration which initially mimicked myasthenia gravis with fluctuating diplopia and ptosis. To the authors' best knowledge, this represents the first report where neurolymphomatosis masquerades as myasthenia gravis and is the second case documenting coinciding cranial nerve with extraocular muscle involvement. The case is presented alongside a systematic review of neurolymphomatosis affecting cranial nerves II, III, IV, VI, including its pathological distribution, modality of diagnosis, treatments, and outcomes.

PMID:40396903 | DOI:10.1080/01676830.2025.2505501


Source: https://pubmed.ncbi.nlm.nih.gov/4039690 ... t9+e462414